Gene

sema6ba

ID

ZDB-GENE-131024-1

Name

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Ba

Symbol

sema6ba Nomenclature History

Previous Names

si:ch211-168n16.1

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to have chemorepellent activity and semaphorin receptor binding activity. Predicted to be involved in several processes, including generation of neurons; neural crest cell migration; and semaphorin-plexin signaling pathway. Predicted to localize to extracellular space and integral component of plasma membrane. Is expressed in brain; forebrain; hindbrain; midbrain; and retinal ganglion cell. Human ortholog(s) of this gene implicated in progressive myoclonus epilepsy. Orthologous to human SEMA6B (semaphorin 6B).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Ebert et al., 2012

Cross-Species Comparison

High Throughput Data

Expression Atlas

Thisse Expression Data

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Hamanaka et al., 2020
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With sema6ba Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Epilepsy, progressive myoclonic, 11	618876

Associated With sema6ba Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001627	Sema domain
Family	IPR027231	Semaphorin
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR036352	Sema domain superfamily