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Gene

adgra3

ID
ZDB-GENE-131003-2
Name
adhesion G protein-coupled receptor A3
Symbol
adgra3 Nomenclature History
Previous Names
  • gpr125
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to enable G protein-coupled receptor activity. Acts upstream of or within convergent extension involved in gastrulation; motor neuron migration; and regulation of establishment of planar polarity. Located in plasma membrane. Is expressed in several structures, including brain; liver; otic vesicle; pectoral fin; and pleuroperitoneal region. Orthologous to human ADGRA3 (adhesion G protein-coupled receptor A3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With adgra3 Human Ortholog
No data available
Associated With adgra3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000203 GPS motif
Domain IPR000483 Cysteine-rich flanking region, C-terminal
Domain IPR001879 GPCR, family 2, extracellular hormone receptor domain
Domain IPR003599 Immunoglobulin subtype
Domain IPR007110 Immunoglobulin-like domain
Domain IPR013098 Immunoglobulin I-set
Domain IPR017981 GPCR, family 2-like
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR032675 Leucine-rich repeat domain superfamily
Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
Homologous_superfamily IPR036445 GPCR family 2, extracellular hormone receptor domain superfamily
Repeat IPR001611 Leucine-rich repeat
Repeat IPR003591 Leucine-rich repeat, typical subtype
Domain Details Per Protein
Protein Length Cysteine-rich flanking region, C-terminal GPCR, family 2, extracellular hormone receptor domain GPCR family 2, extracellular hormone receptor domain superfamily GPCR, family 2-like GPS motif Immunoglobulin I-set Immunoglobulin-like domain Immunoglobulin-like domain superfamily Immunoglobulin-like fold Immunoglobulin subtype Leucine-rich repeat Leucine-rich repeat domain superfamily Leucine-rich repeat, typical subtype
UniProtKB:F1QX89
UniProtKB:S4X0Q8 1346
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations