Gene

si:ch73-139e5.4

ID
ZDB-GENE-130531-31
Name
si:ch73-139e5.4
Symbol
si:ch73-139e5.4 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to have guanylate cyclase activity; natriuretic peptide receptor activity; and peptide hormone binding activity. Predicted to be involved in cGMP biosynthetic process and receptor guanylyl cyclase signaling pathway. Predicted to localize to plasma membrane. Human ortholog(s) of this gene implicated in congenital diarrhea 6. Orthologous to human GUCY2C (guanylate cyclase 2C).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With si:ch73-139e5.4 Human Ortholog
No data available
Associated With si:ch73-139e5.4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018297 Adenylyl cyclase class-4/guanylyl cyclase, conserved site
Domain IPR000719 Protein kinase domain
Domain IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase
Domain IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domain
Domain IPR001828 Receptor, ligand binding region
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR028082 Periplasmic binding protein-like I
Homologous_superfamily IPR029787 Nucleotide cyclase
Domain Details Per Protein
Protein Length Adenylyl cyclase class-3/4/guanylyl cyclase Adenylyl cyclase class-4/guanylyl cyclase, conserved site Nucleotide cyclase Periplasmic binding protein-like I Protein kinase domain Protein kinase-like domain superfamily Receptor, ligand binding region Serine-threonine/tyrosine-protein kinase, catalytic domain
UniProtKB:U3JAG6 1071
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations