Gene
shank1
- ID
- ZDB-GENE-130530-691
- Name
- SH3 and multiple ankyrin repeat domains 1
- Symbol
- shank1 Nomenclature History
- Previous Names
-
- si:dkey-105i19.4
- zmp:0000000688 (1)
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to enable ionotropic glutamate receptor binding activity and synaptic receptor adaptor activity. Predicted to be located in synapse. Predicted to be active in dendritic spine and postsynaptic density. Predicted to colocalize with postsynaptic membrane. Orthologous to human SHANK1 (SH3 and multiple ankyrin repeat domains 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001452 | SH3 domain |
| Domain | IPR001478 | PDZ domain |
| Domain | IPR001660 | Sterile alpha motif domain |
| Domain | IPR032425 | Talin, N-terminal F0 domain |
| Domain | IPR041489 | PDZ domain 6 |
| Family | IPR051569 | SH3 and multiple ankyrin repeat domains protein |
| Homologous_superfamily | IPR013761 | Sterile alpha motif/pointed domain superfamily |
| Homologous_superfamily | IPR036028 | SH3-like domain superfamily |
| Homologous_superfamily | IPR036034 | PDZ superfamily |
| Homologous_superfamily | IPR036770 | Ankyrin repeat-containing domain superfamily |
| Repeat | IPR002110 | Ankyrin repeat |
Domain Details Per Protein
| Protein | Additional Resources | Length | Ankyrin repeat | Ankyrin repeat-containing domain superfamily | PDZ domain | PDZ domain 6 | PDZ superfamily | SH3 and multiple ankyrin repeat domains protein | SH3 domain | SH3-like domain superfamily | Sterile alpha motif domain | Sterile alpha motif/pointed domain superfamily | Talin, N-terminal F0 domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9PQF3 | InterPro | 882 | |||||||||||
| UniProtKB:A0A8M9PRS2 | InterPro | 2469 | |||||||||||
| UniProtKB:A0A8M9Q8Y1 | InterPro | 1807 | |||||||||||
| UniProtKB:A0A8M9PJG1 | InterPro | 883 | |||||||||||
| UniProtKB:A0A8M9Q129 | InterPro | 2449 | |||||||||||
| UniProtKB:A0A8M9PEY7 | InterPro | 2467 | |||||||||||
| UniProtKB:A0A8M9P8G4 | InterPro | 1773 | |||||||||||
| UniProtKB:A0A8M9PQE5 | InterPro | 2461 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
shank1-201
(1)
|
Ensembl | 2,865 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance