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Gene

nppb

ID
ZDB-GENE-130530-642
Name
natriuretic peptide B
Symbol
nppb Nomenclature History
Previous Names
  • si:ch211-215j19.10
  • zmp:0000000639
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to enable hormone activity. Acts upstream of or within atrioventricular canal development; cardiac jelly development; and cardiac muscle cell proliferation. Predicted to be located in extracellular region. Is expressed in atrium; cardiac ventricle; heart; and heart tube. Human ortholog(s) of this gene implicated in atherosclerosis; hypertension; myocardial infarction; obesity; and systolic heart failure. Orthologous to human NPPB (natriuretic peptide B).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
24 figures from 22 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nppb Human Ortholog
No data available
Associated With nppb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR030480 Natriuretic peptide, conserved site
Family IPR000663 Natriuretic peptide
Family IPR002408 Natriuretic peptide, brain type
Domain Details Per Protein
Protein Length Natriuretic peptide Natriuretic peptide, brain type Natriuretic peptide, conserved site
UniProtKB:F1R8L8 129
UniProtKB:D1LXJ0 103
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations