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ZIRC
ZFIN ID: ZDB-GENE-130530-589
Gene Name: zinc finger protein 408
Gene Symbol: znf408
Sequence Ontology ID : SO:0001217

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Previous Name: zmp:0000000586

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(Including Attributions)
Location: Chr: 7 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have metal ion binding activity and nucleic acid binding activity. Involved in retina vasculature development in camera-type eye. Predicted to localize to the nucleus. Human ortholog(s)  ...
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
rmc102 Small Deletion Unknown Unknown CRISPR
rmc103 Small Deletion Unknown Unknown CRISPR
rmc104 Point Mutation Unknown Missense CRISPR
sa15177 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34129 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40962 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    DISEASE ASSOCIATED WITH znf408 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    exudative vitreoretinopathy 6 ?Exudative vitreoretinopathy 6 616468
    retinitis pigmentosa 72 Retinitis pigmentosa 72 616469
    DISEASE ASSOCIATED WITH znf408 VIA EXPERIMENTAL MODELS
    Human Disease Fish Conditions Citations
    exudative vitreoretinopathy y1Tg + MO1-znf408 standard conditions Collin et al., 2013
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process retina vasculature development in camera-type eye (more)
    Cellular Component nucleus (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 4)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA znf408-201 (1) 2474
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM znf408 No data available
    MARKER RELATIONSHIPS
    znf408 Contained in: [BAC] DKEY-23N7 (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001328275 (1)
    Genomic GenBank:BX957256 (1) 227909 bp Blast at MegaBLAST
    Polypeptide UniProtKB:E7FAN3 (1) 764 aa
    Sequence Clusters UniGene:115814 (1)
    Sequence Information (all 10)
    ORTHOLOGY for znf408 ( Chr: 7 )
    CITATIONS (12)