Gene
tgfb5
- ID
- ZDB-GENE-130425-3
- Name
- transforming growth factor, beta 5
- Symbol
- tgfb5 Nomenclature History
- Previous Names
-
- tgfb2l
- zmp:0000000733 (1)
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to have growth factor activity and transforming growth factor beta receptor binding activity. Predicted to be involved in positive regulation of cell division. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in Loeys-Dietz syndrome 4 and colorectal cancer. Is expressed in pharynx. Orthologous to human TGFB2 (transforming growth factor beta 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Abrial et al., 2017
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017948 | Transforming growth factor beta, conserved site |
| Domain | IPR001111 | TGF-beta, propeptide |
| Domain | IPR001839 | Transforming growth factor-beta, C-terminal |
| Family | IPR003940 | Transforming growth factor beta-2 proprotein |
| Family | IPR015615 | Transforming growth factor-beta-related |
| Family | IPR016319 | Transforming growth factor-beta |
| Homologous_superfamily | IPR029034 | Cystine-knot cytokine |
Domain Details Per Protein
| Protein | Length | Cystine-knot cytokine | TGF-beta, propeptide | Transforming growth factor-beta | Transforming growth factor beta-2 proprotein | Transforming growth factor beta, conserved site | Transforming growth factor-beta, C-terminal | Transforming growth factor-beta-related |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9QGK2
|
414 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
tgfb2l-201
(1)
|
Havana | 4267 nt | |
| mRNA |
tgfb2l-202
(1)
|
Havana | 772 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance