ZFIN ID: ZDB-GENE-130411-2
Gene Name: solute carrier family 6 member 14
Gene Symbol: slc6a14    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 11 Mapping Details/Browsers
Description: Predicted to have neurotransmitter:sodium symporter activity. Predicted to localize to the plasma membrane. Human ortholog(s) of this gene implicated in obesity. Is expressed in liver. Orthologous to human SLC6A14 (solute carrier family 6 member 14).
Genome Resources: Alliance (1),  Gene:100150665 (1),  Ensembl(GRCz11):ENSDARG00000029866 (2)
GENE EXPRESSION
All Expression Data: Fig. S3 from Wang et al., 2017
Wild-type Stages, Structures: Adult (90d-730d, breeding adult) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa41817 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH slc6a14 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH slc6a14 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Cellular Component integral component of membrane (more)
    Molecular Function neurotransmitter:sodium symporter activity (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Family IPR000175 Sodium:neurotransmitter symporter
    Homologous_superfamily IPR037272 Sodium:neurotransmitter symporter superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA slc6a14-201 (1)    Ensembl 2000
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM slc6a14 No data available
    MARKER RELATIONSHIPS
    slc6a14 Contained in: [BAC] CH211-158F7 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001326450 (1)
    Genomic GenBank:CU459075 (1) 179501 bp
    Select Tool
    Polypeptide UniProtKB:Q1ECY9 (1) 625 aa
    Sequence Information (all 9)
    ORTHOLOGY for slc6a14 ( Chr: 11 )
    CITATIONS (16)