ZFIN ID: ZDB-GENE-130204-2
Gene Name: zinc finger and AT hook domain containing
Gene Symbol: zfat    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Predicted to have DNA binding activity and DNA-binding transcription factor activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in autoimmune thyroiditis. Orthologous to human ZFAT (zinc finger and AT-hook domain containing).
Genome Resources: Alliance (1),  Gene:566334 (1),  Ensembl(GRCz11):ENSDARG00000077987 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa22840 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36134 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36135 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-zfat N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH zfat HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    {Autoimmune thyroid disease, susceptibility to, 3} 608175
    DISEASE ASSOCIATED WITH zfat VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of transcription, DNA-templated (more)
    Cellular Component nucleus (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA zfat-202 (1)    Ensembl 3701
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM zfat No data available
    MARKER RELATIONSHIPS
    zfat Contained in: [BAC] DKEY-25O19 (1) (order this), DKEY-29H14 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA GenBank:EB908785 (1) 400 nt
    Genomic GenBank:BX571853 (1) 191052 nt
    Select Tool
    Polypeptide UniProtKB:X1WBC8 (1) 1176 aa
    Sequence Information (all 5)
    ORTHOLOGY for zfat ( Chr: 16 )
    CITATIONS (17)