Gene

efl1

ID
ZDB-GENE-130103-6
Name
elongation factor like GTPase 1
Symbol
efl1 Nomenclature History
Previous Names
  • eftud1 (1)
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have GTPase activity and ribosome binding activity. Predicted to be involved in mature ribosome assembly. Predicted to localize to cytosol and ribonucleoprotein complex. Human ortholog(s) of this gene implicated in Shwachman-Diamond syndrome. Orthologous to human EFL1 (elongation factor like GTPase 1).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With efl1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Shwachman-Diamond syndrome 2 617941
Associated With efl1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000640 Elongation factor EFG, domain V-like
Domain IPR000795 Translational (tr)-type GTP-binding domain
Domain IPR004161 Translation elongation factor EFTu-like, domain 2
Domain IPR005225 Small GTP-binding protein domain
Domain IPR041095 Elongation Factor G, domain II
Homologous_superfamily IPR009000 Translation protein, beta-barrel domain superfamily
Homologous_superfamily IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup
Homologous_superfamily IPR020568 Ribosomal protein S5 domain 2-type fold
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR035647 EF-G domain III/V-like
Domain Details Per Protein
Protein Length EF-G domain III/V-like Elongation factor EFG, domain V-like Elongation Factor G, domain II P-loop containing nucleoside triphosphate hydrolase Ribosomal protein S5 domain 2-type fold Ribosomal protein S5 domain 2-type fold, subgroup Small GTP-binding protein domain Translational (tr)-type GTP-binding domain Translation elongation factor EFTu-like, domain 2 Translation protein, beta-barrel domain superfamily
UniProtKB:A0A0R4ITN4 1133
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Citations