ZFIN ID: ZDB-GENE-121207-1
Gene Name: phosphofructokinase, liver a
Gene Symbol: pfkla    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have 6-phosphofructokinase activity; ATP binding activity; and metal ion binding activity. Predicted to be involved in fructose 6-phosphate metabolic process and glycolytic process. Predicted to localize to cytoplasm. Orthologous to human PFKL (phosphofructokinase, liver type).
Genome Resources: Alliance (1),  Gene:570106 (1),  Ensembl(GRCz11):ENSDARG00000060504 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa15186 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21608 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH pfkla HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Hemolytic anemia due to phosphofructokinase deficiency
    DISEASE ASSOCIATED WITH pfkla VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process canonical glycolysis (more)
    Cellular Component 6-phosphofructokinase complex (more)
    Molecular Function 6-phosphofructokinase activity (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA pfkla-202 (1)    Ensembl 2456
    ncRNA pfkla-002 (1)    Ensembl 514
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pfkla No data available
    MARKER RELATIONSHIPS
    pfkla Contained in: [BAC] CH211-241J8 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_693543 (1) 3908 nt
    Genomic GenBank:CR339053 (1) 154689 nt
    Select Tool
    Polypeptide RefSeq:XP_698635 (1) 780 aa
    Sequence Information (all 5)
    ORTHOLOGY for pfkla ( Chr: 9 )
    CITATIONS (14)