Gene

sh3bp1

ID
ZDB-GENE-121128-2
Name
SH3-domain binding protein 1
Symbol
sh3bp1 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to have GTPase activator activity and Rac GTPase binding activity. Predicted to be involved in regulation of Rac protein signal transduction and regulation of actin cytoskeleton organization. Predicted to localize to cytoplasm. Orthologous to human SH3BP1 (SH3 domain binding protein 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sh3bp1 Human Ortholog
No data available
Associated With sh3bp1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000198 Rho GTPase-activating protein domain
Domain IPR004148 BAR domain
Family IPR047165 Rho GTPase-activating protein 17/44/SH3BP1-like
Homologous_superfamily IPR008936 Rho GTPase activation protein
Homologous_superfamily IPR027267 AH/BAR domain superfamily
Domain Details Per Protein
Protein Length AH/BAR domain superfamily BAR domain Rho GTPase-activating protein 17/44/SH3BP1-like Rho GTPase-activating protein domain Rho GTPase activation protein
UniProtKB:E7FFF8 670
UniProtKB:A0A8M9PFG1 600
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations