kcna4

ID

ZDB-GENE-121127-2

Name

potassium voltage-gated channel, shaker-related subfamily, member 4

Symbol

kcna4 Nomenclature History

Previous Names

knca4
zmp:0000001194

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable delayed rectifier potassium channel activity. Predicted to be involved in action potential and potassium ion transmembrane transport. Predicted to act upstream of or within monoatomic ion transmembrane transport; potassium ion transport; and protein homooligomerization. Predicted to be located in cell projection and plasma membrane. Predicted to be part of voltage-gated potassium channel complex. Predicted to be active in axon; dendritic spine; and membrane. Is expressed in heart. Orthologous to human KCNA4 (potassium voltage-gated channel subfamily A member 4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With kcna4 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Microcephaly, cataracts, impaired intellectual development, and dystonia with abnormal striatum	618284

Associated With kcna4 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000210	BTB/POZ domain
Domain	IPR003131	Potassium channel tetramerisation-type BTB domain
Domain	IPR005821	Ion transport domain
Domain	IPR012897	Potassium channel, voltage dependent, Kv1.4, tandem inactivation domain
Family	IPR003968	Potassium channel, voltage dependent, Kv
Family	IPR003972	Potassium channel, voltage dependent, Kv1
Family	IPR020467	Potassium channel, voltage dependent, Kv1.4
Family	IPR028325	Voltage-gated potassium channel
Homologous_superfamily	IPR011333	SKP1/BTB/POZ domain superfamily
Homologous_superfamily	IPR027359	Voltage-dependent channel domain superfamily
Homologous_superfamily	IPR037065	Potassium channel, voltage dependent, Kv1.4, tandem inactivation domain superfamily