Gene
ttbk2a
- ID
- ZDB-GENE-120928-3
- Name
- tau tubulin kinase 2a
- Symbol
- ttbk2a Nomenclature History
- Previous Names
-
- ttbk2
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to have protein serine/threonine kinase activity. Predicted to be involved in cilium assembly and peptidyl-serine phosphorylation. Predicted to localize to several cellular components, including ciliary basal body; ciliary transition zone; and nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 11. Orthologous to human TTBK2 (tau tubulin kinase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| spinocerebellar ataxia type 11 | Alliance | Spinocerebellar ataxia 11 | 604432 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Casein Kinase 1 Ser/Thr Protein Kinase | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:E7FE66
|
1193 | ||||
|
UniProtKB:A0A2R8QH39
|
1082 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ttbk2a-201
(1)
|
Ensembl | 4,231 nt | ||
| mRNA |
ttbk2a-202
(1)
|
Ensembl | 3,951 nt | ||
| mRNA |
ttbk2a-203
(1)
|
Ensembl | 3,618 nt | ||
| mRNA |
ttbk2a-204
(1)
|
Ensembl | 1,296 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance