Gene
sting1
- ID
- ZDB-GENE-120921-1
- Name
- stimulator of interferon response cGAMP interactor 1
- Symbol
- sting1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to have cyclic-GMP-AMP binding activity and cyclic-di-GMP binding activity. Involved in several processes, including NIK/NF-kappaB signaling; defense response to other organism; and positive regulation of defense response to virus by host. Localizes to endoplasmic reticulum. Human ortholog(s) of this gene implicated in STING-associated vasculopathy with onset in infancy. Orthologous to human STING1 (stimulator of interferon response cGAMP interactor 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| STING-associated vasculopathy with onset in infancy | Alliance | STING-associated vasculopathy, infantile-onset | 615934 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Stimulator of interferon genes protein | Stimulator of interferon genes protein, C-terminal | Stimulator of interferon genes protein, C-terminal domain superfamily |
|---|---|---|---|---|
|
UniProtKB:E7F4N7
|
398 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
tmem173-201
(1)
|
Havana | 1583 nt |
Interactions and Pathways
No data available
Plasmids