header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-120919-4
Gene Name: itchy E3 ubiquitin protein ligase a
Gene Symbol: itcha
Sequence Ontology ID : SO:0001217

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name: itch

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 6 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have ubiquitin protein ligase activity. Predicted to be involved in positive regulation of protein catabolic process; proteasome-mediated ubiquitin-dependent protein catabolic process;  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa20834 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa26849 Point Mutation Unknown Premature Stop ENU
    Targeting reagents:
    PHENOTYPE
    Data: Fig. 3 from Angers et al., 2014
    Observed in:
    DISEASE ASSOCIATED WITH itcha HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Autoimmune disease, multisystem, with facial dysmorphism 613385
    DISEASE ASSOCIATED WITH itcha VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process ubiquitin-dependent protein catabolic process (more)
    Cellular Component cytoplasm (more)
    Molecular Function ligase activity (more)
    GO Terms (all 10)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA itcha-002 (1) 585
    mRNA itcha-202 (1) 3374
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM itcha No data available
    MARKER RELATIONSHIPS
    itcha Contained in: [BAC] CH211-60J9 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001287095 (1) 2792 bp
    Genomic GenBank:CU929339 (1) 181638 bp
    Select Tool
    Polypeptide UniProtKB:U6C7X6 (1) 851 aa
    Sequence Information (all 11)
    ORTHOLOGY for itcha ( Chr: 6 )
    CITATIONS (17)