Gene

plcl2

ID

ZDB-GENE-120426-4

Name

phospholipase C like 2

Symbol

plcl2 Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to enable phosphatidylinositol-4,5-bisphosphate phospholipase C activity. Predicted to act upstream of or within intracellular signal transduction and lipid catabolic process. Predicted to be located in cytoplasm.

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With plcl2 Human Ortholog

No data available

Associated With plcl2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000008	C2 domain
Domain	IPR000909	Phosphatidylinositol-specific phospholipase C, X domain
Domain	IPR001711	Phospholipase C, phosphatidylinositol-specific, Y domain
Domain	IPR001849	Pleckstrin homology domain
Domain	IPR015359	Phosphoinositide-specific phospholipase C, EF-hand-like domain
Family	IPR001192	Phosphoinositide phospholipase C family
Homologous_superfamily	IPR011992	EF-hand domain pair
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR017946	PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily
Homologous_superfamily	IPR035892	C2 domain superfamily

Domain Details Per Protein

Protein	Additional Resources	Length	C2 domain	C2 domain superfamily	EF-hand domain pair	PH-like domain superfamily	Phosphatidylinositol-specific phospholipase C, X domain	Phosphoinositide phospholipase C family	Phosphoinositide-specific phospholipase C, EF-hand-like domain	Phospholipase C, phosphatidylinositol-specific, Y domain	PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily	Pleckstrin homology domain
UniProtKB:E7F5P3	InterPro	1097
UniProtKB:A0A8M1RS83	InterPro	1097

Transcripts

Genome Browsers

NCBI

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	plcl2-201 (1) Ensembl	Ensembl	3,132 nt	Select Tool ZFIN BLAST
mRNA	plcl2-202 (1) Ensembl	Ensembl	3,186 nt	Select Tool ZFIN BLAST
mRNA	plcl2-203 (1) Ensembl	Ensembl	2,757 nt	Select Tool ZFIN BLAST
mRNA	plcl2-204 (1) Ensembl	Ensembl	3,093 nt	Select Tool ZFIN BLAST
mRNA	plcl2-205 (1) Ensembl	Ensembl	3,234 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations