Gene

plcl2

ID
ZDB-GENE-120426-4
Name
phospholipase C like 2
Symbol
plcl2 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Unmapped
Description
Predicted to have GABA receptor binding activity; inositol 1,4,5 trisphosphate binding activity; and phosphatidylinositol phospholipase C activity. Predicted to be involved in intracellular signal transduction; lipid catabolic process; and regulation of GABAergic synaptic transmission. Predicted to localize to integral component of membrane.
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With plcl2 Human Ortholog
No data available
Associated With plcl2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000008 C2 domain
Domain IPR000909 Phosphatidylinositol-specific phospholipase C, X domain
Domain IPR001711 Phospholipase C, phosphatidylinositol-specific, Y domain
Domain IPR001849 Pleckstrin homology domain
Domain IPR015359 Phosphoinositide-specific phospholipase C, EF-hand-like domain
Family IPR001192 Phosphoinositide phospholipase C family
Family IPR028382 Inactive phospholipase C-like protein 2
Homologous_superfamily IPR011992 EF-hand domain pair
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily
Homologous_superfamily IPR035892 C2 domain superfamily
Domain Details Per Protein
Protein Length C2 domain C2 domain superfamily EF-hand domain pair Inactive phospholipase C-like protein 2 PH-like domain superfamily Phosphatidylinositol-specific phospholipase C, X domain Phosphoinositide phospholipase C family Phosphoinositide-specific phospholipase C, EF-hand-like domain Phospholipase C, phosphatidylinositol-specific, Y domain PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily Pleckstrin homology domain
UniProtKB:E7F5P3 1097
UniProtKB:A0A2R8RQR9 1043
UniProtKB:A0A2R8RVV2 1077
UniProtKB:A0A2R8RHH4 1030
UniProtKB:A0A2R8Q1Z0 1061
Transcripts
Genome Browsers
No data available
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations