Gene
plcl2
- ID
- ZDB-GENE-120426-4
- Name
- phospholipase C like 2
- Symbol
- plcl2 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Unmapped
- Description
- Predicted to have GABA receptor binding activity; inositol 1,4,5 trisphosphate binding activity; and phosphatidylinositol phospholipase C activity. Predicted to be involved in intracellular signal transduction; lipid catabolic process; and regulation of GABAergic synaptic transmission. Predicted to localize to integral component of membrane.
- Genome Resources
- Note
- None
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000008 | C2 domain |
| Domain | IPR000909 | Phosphatidylinositol-specific phospholipase C, X domain |
| Domain | IPR001711 | Phospholipase C, phosphatidylinositol-specific, Y domain |
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR015359 | Phosphoinositide-specific phospholipase C, EF-hand-like domain |
| Family | IPR001192 | Phosphoinositide phospholipase C family |
| Family | IPR028382 | Inactive phospholipase C-like protein 2 |
| Homologous_superfamily | IPR011992 | EF-hand domain pair |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR017946 | PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily |
| Homologous_superfamily | IPR035892 | C2 domain superfamily |
Domain Details Per Protein
| Protein | Length | C2 domain | C2 domain superfamily | EF-hand domain pair | Inactive phospholipase C-like protein 2 | PH-like domain superfamily | Phosphatidylinositol-specific phospholipase C, X domain | Phosphoinositide phospholipase C family | Phosphoinositide-specific phospholipase C, EF-hand-like domain | Phospholipase C, phosphatidylinositol-specific, Y domain | PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily | Pleckstrin homology domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:E7F5P3
|
1097 | |||||||||||
|
UniProtKB:A0A2R8RQR9
|
1043 | |||||||||||
|
UniProtKB:A0A2R8RVV2
|
1077 | |||||||||||
|
UniProtKB:A0A2R8RHH4
|
1030 | |||||||||||
|
UniProtKB:A0A2R8Q1Z0
|
1061 |
- Genome Browsers
- No data available
Interactions and Pathways
No data available
Plasmids
No data available
- Gene Tree
- Ensembl