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ZIRC
ZFIN ID: ZDB-GENE-120411-11
Gene Name: dedicator of cytokinesis 6
Gene Symbol: dock6    Nomenclature History

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Previous Names: si:dkey-114l24.1, unm_sa1010, unm_sa899

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have guanyl-nucleotide exchange factor activity. Predicted to be involved in small GTPase mediated signal transduction. Human ortholog(s) of this gene implicated in Adams-Oliver syndrome. Orthologous to human DOCK6 (dedicator of cytokinesis 6).
Genome Resources: Alliance (1),  Gene:553459 (1),  Ensembl(GRCz11):ENSDARG00000035706 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa899 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa1010 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa6922 Point Mutation Unknown Premature Stop ENU
    sa12512 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa26161 Point Mutation Unknown Premature Stop ENU
    sa33330 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40178 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH dock6 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Adams-Oliver syndrome Alliance Adams-Oliver syndrome 2 614219
    DISEASE ASSOCIATED WITH dock6 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process small GTPase mediated signal transduction (more)
    Molecular Function guanyl-nucleotide exchange factor activity (more)
    GO Terms (all 2)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA dock6-201 (1)    Ensembl 7012
    ncRNA dock6-002 (1)    Ensembl 870
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dock6 No data available
    MARKER RELATIONSHIPS
    dock6 Contained in: [BAC] DKEY-114L24 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XR_660513 (1)
    Genomic GenBank:CT583658 (1) 144554 bp
    Select Tool
    Polypeptide UniProtKB:F1Q4R1 (1) 2114 aa
    Sequence Clusters UniGene:106311 (1)
    Sequence Information (all 12)
    ORTHOLOGY for dock6 ( Chr: 3 )
    CITATIONS (17)