Gene

fmnl1a

ID
ZDB-GENE-120215-83
Name
formin-like 1a
Symbol
fmnl1a Nomenclature History
Previous Names
  • si:dkey-234e12.3
  • unm_sa3326
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have actin filament binding activity. Predicted to be involved in cell migration; cortical actin cytoskeleton organization; and regulation of cell shape. Predicted to localize to cytosol. Is expressed in several structures, including nervous system; notochord; optic cup; pharynx; and trunk. Orthologous to human FMNL1 (formin like 1).
Genome Resources
Note
None
Expression
All Expression Data
6 figures from Santos-Ledo et al., 2013
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fmnl1a Human Ortholog
No data available
Associated With fmnl1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR010472 Formin, FH3 domain
Domain IPR010473 Formin, GTPase-binding domain
Domain IPR014767 Diaphanous autoregulatory (DAD) domain
Domain IPR014768 Rho GTPase-binding/formin homology 3 (GBD/FH3) domain
Domain IPR015425 Formin, FH2 domain
Family IPR027657 Formin-like protein 1
Family IPR043592 Formin-like protein
Homologous_superfamily IPR016024 Armadillo-type fold
Homologous_superfamily IPR042201 Formin, FH2 domain superfamily
Domain Details Per Protein
Protein Length Armadillo-type fold Diaphanous autoregulatory (DAD) domain Formin, FH2 domain Formin, FH2 domain superfamily Formin, FH3 domain Formin, GTPase-binding domain Formin-like protein Formin-like protein 1 Rho GTPase-binding/formin homology 3 (GBD/FH3) domain
UniProtKB:A0A2R8QRD9 1056
UniProtKB:I3ITQ8 1085
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Citations