Gene
arhgap44a
- ID
- ZDB-GENE-120215-49
- Name
- Rho GTPase activating protein 44a
- Symbol
- arhgap44a Nomenclature History
- Previous Names
-
- si:ch211-114m9.1
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to enable GTPase activator activity. Predicted to be involved in negative regulation of Rac protein signal transduction; regulation of actin cytoskeleton organization; and regulation of dendritic spine morphogenesis. Predicted to act upstream of or within positive regulation of GTPase activity and signal transduction. Predicted to be located in dendrite; presynapse; and recycling endosome. Predicted to be active in several cellular components, including dendritic spine; postsynaptic density; and presynaptic active zone. Human ortholog(s) of this gene implicated in acquired immunodeficiency syndrome and skin melanoma. Orthologous to human ARHGAP44 (Rho GTPase activating protein 44).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | AH/BAR domain superfamily | BAR domain | Rho GTPase-activating protein 17/44/SH3BP1-like | Rho GTPase-activating protein domain | Rho GTPase activation protein |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9PTP9 | InterPro | 741 | |||||
| UniProtKB:A0A8M3AY97 | InterPro | 984 | |||||
| UniProtKB:A0A8M9Q4C6 | InterPro | 990 | |||||
| UniProtKB:A0A8M9Q151 | InterPro | 990 | |||||
| UniProtKB:A0A8M9PXV6 | InterPro | 984 | |||||
| UniProtKB:A0A8M9Q8P0 | InterPro | 888 | |||||
| UniProtKB:A0A8M9Q4C8 | InterPro | 810 | |||||
| UniProtKB:A0A8M3AQV7 | InterPro | 940 | |||||
| UniProtKB:A0A8M9PQH5 | InterPro | 888 | |||||
| UniProtKB:A0A8M9P8I2 | InterPro | 940 | |||||
| UniProtKB:A0AB32TLA2 | InterPro | 887 | |||||
| UniProtKB:A0AB32TMX5 | InterPro | 783 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
si:ch211-114m9.1-201
(1)
|
Ensembl | 3,845 nt |
Interactions and Pathways
No data available
Plasmids
No data available