ZFIN ID: ZDB-GENE-120215-23
Gene Name: activin A receptor type 2Ab
Gene Symbol: acvr2ab    Nomenclature History

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Previous Name: si:dkey-264o13.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have activin binding activity and activin-activated receptor activity. Predicted to be involved in activin receptor signaling pathway; cellular response to growth factor stimulus; and protein phosphorylation. Predicted to localize to activin receptor complex. Human ortholog(s) of this gene implicated in colon cancer. Orthologous to human ACVR2A (activin A receptor type 2A).
Genome Resources: Alliance (1),  Gene:100331014 (1),  Ensembl(GRCz11):ENSDARG00000104700 (1)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa12982 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18285 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa33786 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-acvr2ab
    2
    CRISPR2-acvr2ab
    2
    MO1-acvr2ab N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH acvr2ab HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH acvr2ab VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process phosphorylation (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ATP binding (more)
    GO Terms (all 20)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA acvr2ab-201 (1)    Ensembl 1481
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM acvr2ab No data available
    MARKER RELATIONSHIPS
    acvr2ab Contained in: [BAC] DKEY-264O13 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_005168700 (1)
    Genomic GenBank:CU570699 (1) 85234 nt
    Select Tool
    Polypeptide UniProtKB:A0A0R4ISZ9 (1) 439 aa
    Sequence Information (all 8)
    ORTHOLOGY for acvr2ab ( Chr: 6 )
    CITATIONS (19)