Gene
dlg5b.1
- ID
- ZDB-GENE-120206-4
- Name
- discs, large homolog 5b (Drosophila), tandem duplicate 1
- Symbol
- dlg5b.1 Nomenclature History
- Previous Names
-
- dlg5b.3
- dlg5b
- zmp:0000000771 (1)
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to be involved in negative regulation of hippo signaling. Predicted to act upstream of or within regulation of apoptotic process. Predicted to be located in membrane. Orthologous to human DLG5 (discs large MAGUK scaffold protein 5).
- Genome Resources
- Note
-
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Yuksel-Vogel-Bauser syndrome | 620703 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001315 | CARD domain |
| Domain | IPR001452 | SH3 domain |
| Domain | IPR001478 | PDZ domain |
| Domain | IPR006907 | Disks large homolog 5, N-terminal |
| Domain | IPR008144 | Guanylate kinase-like domain |
| Domain | IPR008145 | Guanylate kinase/L-type calcium channel beta subunit |
| Domain | IPR035537 | Disks large homologue 5, SH3 domain |
| Family | IPR053004 | MAGUK Family Regulators of Signaling Pathways |
| Homologous_superfamily | IPR011029 | Death-like domain superfamily |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036028 | SH3-like domain superfamily |
| Homologous_superfamily | IPR036034 | PDZ superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | CARD domain | Death-like domain superfamily | Disks large homolog 5, N-terminal | Disks large homologue 5, SH3 domain | Guanylate kinase-like domain | Guanylate kinase/L-type calcium channel beta subunit | MAGUK Family Regulators of Signaling Pathways | PDZ domain | PDZ superfamily | P-loop containing nucleoside triphosphate hydrolase | SH3 domain | SH3-like domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9QF19 | InterPro | 1907 | ||||||||||||
| UniProtKB:A0A8M3BEE2 | InterPro | 1881 | ||||||||||||
| UniProtKB:A0A8M9QN58 | InterPro | 1830 | ||||||||||||
| UniProtKB:A0A8M9QJE1 | InterPro | 1804 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
dlg5b.1-201
(1)
|
Ensembl | 6,650 nt | ||
| mRNA |
dlg5b.1-202
(1)
|
Ensembl | 1,900 nt | ||
| mRNA |
dlg5b.1-203
(1)
|
Ensembl | 6,081 nt | ||
| mRNA |
dlg5b.1-204
(1)
|
Ensembl | 6,159 nt | ||
| mRNA |
dlg5b.1-205
(1)
|
Ensembl | 5,360 nt | ||
| mRNA |
dlg5b.1-206
(1)
|
Ensembl | 5,088 nt |
Interactions and Pathways
No data available
Plasmids
No data available