Gene
ank2a
- ID
- ZDB-GENE-111215-3
- Name
- ankyrin 2a, neuronal
- Symbol
- ank2a Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to act upstream of or within signal transduction. Predicted to be located in cytoplasm; cytoskeleton; and membrane. Human ortholog(s) of this gene implicated in ankyrin-B-related cardiac arrhythmia; atrial fibrillation; long QT syndrome; and sick sinus syndrome. Orthologous to human ANK2 (ankyrin 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| ankyrin-B-related cardiac arrhythmia | Alliance | Cardiac arrhythmia, ankyrin-B-related | 600919 |
| ankyrin-B-related cardiac arrhythmia | Alliance | Long QT syndrome 4 | 600919 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000488 | Death domain |
| Domain | IPR000906 | ZU5 domain |
| Domain | IPR040745 | Ankyrin, UPA domain |
| Family | IPR051165 | Multifunctional Ankyrin Repeat Domain-Containing Protein |
| Homologous_superfamily | IPR011029 | Death-like domain superfamily |
| Homologous_superfamily | IPR036770 | Ankyrin repeat-containing domain superfamily |
| Repeat | IPR002110 | Ankyrin repeat |
Domain Details Per Protein
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance