Gene
trpm6
- ID
- ZDB-GENE-111212-1
- Name
- transient receptor potential cation channel, subfamily M, member 6
- Symbol
- trpm6 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have ATP binding activity; cation channel activity; and protein serine/threonine kinase activity. Predicted to be involved in several processes, including cation transport; protein phosphorylation; and protein tetramerization. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in intestinal hypomagnesemia 1 and metal metabolism disorder. Is expressed in several structures, including digestive system; heart; opercular flap; pleuroperitoneal region; and scale. Orthologous to human TRPM6 (transient receptor potential cation channel subfamily M member 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| intestinal hypomagnesemia 1 | Alliance | Hypomagnesemia 1, intestinal | 602014 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR004166 | Alpha-type protein kinase, alpha-kinase domain |
| Domain | IPR005821 | Ion transport domain |
| Domain | IPR032415 | TRPM, tetramerisation domain |
| Domain | IPR041491 | TRPM, SLOG domain |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR037162 | TRPM, tetramerisation domain superfamily |
Domain Details Per Protein
| Protein | Length | Alpha-type protein kinase, alpha-kinase domain | Ion transport domain | Protein kinase-like domain superfamily | TRPM, SLOG domain | TRPM, tetramerisation domain | TRPM, tetramerisation domain superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A0G2KJE9
|
1530 | ||||||
|
UniProtKB:G4WAZ8
|
1875 | ||||||
|
UniProtKB:A0A8M9Q2T2
|
1875 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available