ZFIN ID: ZDB-GENE-111102-3
Gene Name: microtubule associated protein 1
Gene Symbol: map11    Nomenclature History

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Previous Names: gb:dn856615 (1), si:dkey-3k24.5

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to have alpha-tubulin binding activity. Involved in regulation of cell population proliferation. Predicted to localize to midbody and mitotic spindle. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly. Orthologous to human MAP11 (microtubule associated protein 11).
Genome Resources: Alliance (1),  Gene:100003958 (1),  Ensembl(GRCz11):ENSDARG00000078891 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
bgu1 Indel Unknown Frameshift, Premature Stop CRISPR
bgu2 Indel Unknown Unknown CRISPR
sa20944 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34071 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-map11 1
    CRISPR2-map11 1
    MO1-map11 N/A 1
    DISEASE ASSOCIATED WITH map11 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    ?Microcephaly 25, primary, autosomal recessive 618351
    DISEASE ASSOCIATED WITH map11 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of cell population proliferation (more)
    Cellular Component midbody (more)
    Molecular Function alpha-tubulin binding (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA si:dkey-3k24.5-201 (1)    Ensembl 5070
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM map11 No data available
    MARKER RELATIONSHIPS
    map11 Contained in: [BAC] DKEY-3K24 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_001339293 (1) 5228 nt
    Genomic GenBank:CR848737 (1) 158396 nt
    Select Tool
    Polypeptide UniProtKB:E7F240 (1) 595 aa
    Sequence Information (all 11)
    ORTHOLOGY for map11 ( Chr: 7 )
    CITATIONS (16)