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Gene

ano3

ID
ZDB-GENE-111031-3
Name
anoctamin 3
Symbol
ano3 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to enable intracellular calcium activated chloride channel activity. Predicted to be involved in chloride transmembrane transport. Predicted to act upstream of or within calcium activated phospholipid scrambling. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in head. Human ortholog(s) of this gene implicated in dystonia 24. Orthologous to human ANO3 (anoctamin 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Zech et al., 2015
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ano3 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
dystonia 24 Alliance Dystonia 24 615034
Associated With ano3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR032394 Anoctamin, dimerisation domain
Family IPR007632 Anoctamin
Family IPR031292 Anoctamin-3
Domain Details Per Protein
Protein Length Anoctamin Anoctamin-3 Anoctamin, dimerisation domain
UniProtKB:X1WC49 988
UniProtKB:Q566T3 701
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations