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Gene

fat2

ID
ZDB-GENE-111031-1
Name
FAT atypical cadherin 2
Symbol
fat2 Nomenclature History
Previous Names
  • fk09f07
  • wu:fk09f07
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to enable calcium ion binding activity. Predicted to be involved in cell-cell adhesion. Predicted to act upstream of or within homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be active in adherens junction. Is expressed in cerebellum; granule cell; hindbrain; and optic tectum. Human ortholog(s) of this gene implicated in spinocerebellar ataxia 45. Orthologous to human FAT2 (FAT atypical cadherin 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Takeuchi et al., 2017
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fat2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
spinocerebellar ataxia 45 Alliance Spinocerebellar ataxia 45 617769
Associated With fat2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020894 Cadherin conserved site
Domain IPR000742 EGF-like domain
Domain IPR001791 Laminin G domain
Domain IPR002126 Cadherin-like
Homologous_superfamily IPR013320 Concanavalin A-like lectin/glucanase domain superfamily
Homologous_superfamily IPR015919 Cadherin-like superfamily
Domain Details Per Protein
Protein Length Cadherin conserved site Cadherin-like Cadherin-like superfamily Concanavalin A-like lectin/glucanase domain superfamily EGF-like domain Laminin G domain
UniProtKB:E7FB42 4342
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations