Gene

svep1

ID
ZDB-GENE-110726-1
Name
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
Symbol
svep1 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to enable calcium ion binding activity. Involved in several processes, including epidermis development; epithelial cell-cell adhesion; and lymph vessel morphogenesis. Acts upstream of or within epidermal cell differentiation and lymph vessel development. Predicted to be located in extracellular region. Is expressed in fin bud; pharyngeal arch 3-7; and trunk. Orthologous to human SVEP1 (sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Kärpanen et al., 2017
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With svep1 Human Ortholog
No data available
Associated With svep1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR013032 EGF-like, conserved site
Conserved_site IPR018097 EGF-like calcium-binding, conserved site
Domain IPR000436 Sushi/SCR/CCP domain
Domain IPR000742 EGF-like domain
Domain IPR001881 EGF-like calcium-binding domain
Domain IPR002035 von Willebrand factor, type A
Domain IPR003410 HYR domain
Domain IPR011641 Tyrosine-protein kinase ephrin type A/B receptor-like
Family IPR001759 Pentraxin-related
Homologous_superfamily IPR009030 Growth factor receptor cysteine-rich domain superfamily
Homologous_superfamily IPR013320 Concanavalin A-like lectin/glucanase domain superfamily
Homologous_superfamily IPR035976 Sushi/SCR/CCP superfamily
Homologous_superfamily IPR036465 von Willebrand factor A-like domain superfamily
PTM IPR000152 EGF-type aspartate/asparagine hydroxylation site
Domain Details Per Protein
Protein Length Concanavalin A-like lectin/glucanase domain superfamily EGF-like calcium-binding, conserved site EGF-like calcium-binding domain EGF-like, conserved site EGF-like domain EGF-type aspartate/asparagine hydroxylation site Growth factor receptor cysteine-rich domain superfamily HYR domain Pentraxin-related Sushi/SCR/CCP domain Sushi/SCR/CCP superfamily Tyrosine-protein kinase ephrin type A/B receptor-like von Willebrand factor A-like domain superfamily von Willebrand factor, type A
UniProtKB:A0A1D5NSM8 3615
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations