col21a1

ID

ZDB-GENE-110607-3

Name

collagen, type XXI, alpha 1

Symbol

col21a1 Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 13 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to be part of collagen trimer. Predicted to be active in collagen-containing extracellular matrix. Is expressed in trunk. Human ortholog(s) of this gene implicated in cocaine dependence. Orthologous to human COL21A1 (collagen type XXI alpha 1 chain).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Malbouyres et al., 2022

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With col21a1 Human Ortholog

No data available

Associated With col21a1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR002035	von Willebrand factor, type A
Domain	IPR048287	Thrombospondin-like, N-terminal domain
Family	IPR050149	Collagen superfamily
Homologous_superfamily	IPR013320	Concanavalin A-like lectin/glucanase domain superfamily
Homologous_superfamily	IPR036465	von Willebrand factor A-like domain superfamily
Repeat	IPR008160	Collagen triple helix repeat

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:E7FB76	InterPro	664
UniProtKB:A0A8M6Z408	InterPro	480
UniProtKB:A0A8M6Z2G5	InterPro	965
UniProtKB:A0A8M1RDX1	InterPro	968
UniProtKB:A0AB32T719	InterPro	947