ZFIN ID: ZDB-GENE-110512-2
Gene Name: SNF2 histone linker PHD RING helicase
Gene Symbol: shprh    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Predicted to have ubiquitin protein ligase activity. Predicted to be involved in cellular response to DNA damage stimulus and protein polyubiquitination. Predicted to localize to the nucleosome and nucleus. Orthologous to human SHPRH (SNF2 histone linker PHD RING helicase).
Genome Resources: Alliance (1),  Gene:560526 (1),  Ensembl(GRCz11):ENSDARG00000075884 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa22999 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36315 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa42868 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-shprh N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH shprh HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH shprh VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process nucleosome assembly (more)
    Cellular Component nucleosome (more)
    Molecular Function ATP binding (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Conserved_site IPR017907 Zinc finger, RING-type, conserved site
    Conserved_site IPR019786 Zinc finger, PHD-type, conserved site
    Domain IPR000330 SNF2-related, N-terminal domain
    Domain IPR001650 Helicase, C-terminal
    Domain IPR001841 Zinc finger, RING-type
    Domain IPR001965 Zinc finger, PHD-type
    Domain IPR005818 Linker histone H1/H5, domain H15
    Domain IPR014001 Helicase superfamily 1/2, ATP-binding domain
    Domain IPR027370 RING-type zinc-finger, LisH dimerisation motif
    Homologous_superfamily IPR011011 Zinc finger, FYVE/PHD-type
    Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
    Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
    Homologous_superfamily IPR036388 Winged helix-like DNA-binding domain superfamily
    Homologous_superfamily IPR036390 Winged helix DNA-binding domain superfamily
    Homologous_superfamily IPR038718 SNF2-like, N-terminal domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA shprh-202 (1)    Ensembl 5652
    ncRNA shprh-002 (1)    Ensembl 505
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM shprh No data available
    MARKER RELATIONSHIPS
    shprh Contained in: [BAC] CH211-278P9 (1), DKEYP-110A12 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_003200310 (1)
    Genomic GenBank:BX296541 (1) 157802 nt
    Select Tool
    Polypeptide UniProtKB:A0A2R8QPQ7 (1) 1674 aa
    Sequence Information (all 14)
    ORTHOLOGY for shprh ( Chr: 17 )
    CITATIONS (16)