ZFIN ID: ZDB-GENE-110421-4
Gene Name: mannan-binding lectin serine peptidase 1
Gene Symbol: masp1    Nomenclature History

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Previous Name: si:dkeyp-75c7.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 15 Mapping Details/Browsers
Description: Predicted to have serine-type endopeptidase activity. Involved in cranial skeletal system development; heart development; and neural crest cell migration. Localizes to cytoplasm. Is expressed in central nervous system; heart; and post-vent region. Human ortholog(s) of this gene implicated in 3MC syndrome 1. Orthologous to human MASP1 (mannan binding lectin serine peptidase 1).
Genome Resources: Alliance (1),  Gene:100002060 (1),  Ensembl(GRCz11):ENSDARG00000068726 (2)
GENE EXPRESSION
All Expression Data: 4 figures from 2 publications
Wild-type Stages, Structures: Cleavage:4-cell (1.0h-1.25h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-masp1 N/A 1
MO2-masp1 N/A 1
MO3-masp1 N/A 1
MO4-masp1 N/A 1
DISEASE ASSOCIATED WITH masp1 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
3MC syndrome 1 Alliance 3MC syndrome 1 257920
DISEASE ASSOCIATED WITH masp1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process neural crest cell migration (more)
Cellular Component cytoplasm (more)
Molecular Function calcium ion binding (more)
GO Terms (all 14)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA masp1-202 (1)    Ensembl 2468
masp1-204 (1)    Ensembl 1415
ncRNA masp1-002 (1)    Ensembl 692
masp1-003 (1)    Ensembl 686
Browsers: NCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM masp1 No data available
MARKER RELATIONSHIPS
masp1 Contained in: [BAC] DKEYP-75C7 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:XM_001341900 (1)
Genomic GenBank:BX571739 (1) 139312 nt
Select Tool
Polypeptide UniProtKB:E7FDS3 (1) 766 aa
Sequence Information (all 17)
ORTHOLOGY for masp1 ( Chr: 15 )
CITATIONS (17)