ZFIN ID: ZDB-GENE-110421-3
Gene Name: glutamate receptor, metabotropic 8b
Gene Symbol: grm8b    Nomenclature History

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Previous Names: grm8a, mglur8b (1), si:dkey-56n2.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 25 Mapping Details/Browsers
Description: Predicted to have group III metabotropic glutamate receptor activity. Predicted to be involved in G protein-coupled glutamate receptor signaling pathway and regulation of glutamatergic synaptic transmission. Predicted to localize to integral component of plasma membrane. Is expressed in brain and sensory system. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder; autistic disorder; and schizophrenia. Orthologous to human GRM8 (glutamate metabotropic receptor 8).
Genome Resources: Alliance (1),  Gene:569768 (1),  Ensembl(GRCz11):ENSDARG00000076508 (2)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH grm8b HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH grm8b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process G protein-coupled receptor signaling pathway (more)
Cellular Component integral component of membrane (more)
Molecular Function G protein-coupled receptor activity (more)
GO Terms (all 11)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA grm8b-201 (1)    Ensembl 3939
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM grm8b No data available
MARKER RELATIONSHIPS
grm8b Contained in: [BAC] DKEY-30J9 (1) (order this), DKEY-42P14 (1) (order this), DKEY-56N2 (1) (order this), DKEY-193L23 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001287539 (1) 2738 nt
Genomic GenBank:CR376855 (1) 219164 nt Blast at MegaBLAST
Polypeptide UniProtKB:E7F4Z5 (1) 907 aa
Sequence Information (all 15)
ORTHOLOGY for grm8b ( Chr: 25 )
CITATIONS (19)