ZFIN ID: ZDB-GENE-110421-2
Gene Name: glutamate receptor, metabotropic 8a
Gene Symbol: grm8a    Nomenclature History

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Previous Names: grm8b, mglur8a (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 4 Mapping Details/Browsers
Description: Predicted to have group III metabotropic glutamate receptor activity. Predicted to be involved in G protein-coupled glutamate receptor signaling pathway and regulation of glutamatergic synaptic transmission. Predicted to localize to integral component of plasma membrane. Is expressed in brain and retinal neural layer. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder; autistic disorder; and schizophrenia. Orthologous to human GRM8 (glutamate metabotropic receptor 8).
Genome Resources: Alliance (1),  Ensembl(GRCz11):ENSDARG00000077654 (2)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH grm8a HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH grm8a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process G protein-coupled receptor signaling pathway (more)
Cellular Component integral component of membrane (more)
Molecular Function G protein-coupled receptor activity (more)
GO Terms (all 11)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA grm8a-202 (1)    Ensembl 1010
Browsers: EnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM grm8a No data available
MARKER RELATIONSHIPS
grm8a Contained in: [BAC] CH73-46K5 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA GenBank:EH586272 (1) 846 nt
Genomic GenBank:CU928073 (1) 95687 nt
Select Tool
Polypeptide UniProtKB:E7FH00 (1) 909 aa
Sequence Information (all 6)
ORTHOLOGY for grm8a ( Chr: 4 )
CITATIONS (17)