ZFIN ID: ZDB-GENE-110411-7
Gene Name: fyn-related Src family tyrosine kinase
Gene Symbol: frk    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: frk (2), frka (1), fynrk, sb:eu490, si:ch1073-112f1.1

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 20 Mapping Details/Browsers
Description: Predicted to have non-membrane spanning protein tyrosine kinase activity and signaling receptor binding activity. Predicted to be involved in several processes, including peptidyl-tyrosine autophosphorylation; regulation of cell population proliferation; and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to localize to extrinsic component of cytoplasmic side of plasma membrane. Orthologous to human FRK (fyn related Src family tyrosine kinase).
Genome Resources: Alliance (1),  Ensembl(GRCz11):ENSDARG00000027807 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2005 [eu490]
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa43361 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH frk HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH frk VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process phosphorylation (more)
    Cellular Component extrinsic component of cytoplasmic side of plasma membrane (more)
    Molecular Function ATP binding (more)
    GO Terms (all 16)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA frk-202 (1)    Ensembl 1854
    Browsers: EnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM frk No data available
    MARKER RELATIONSHIPS
    frk Contained in: [Fosmid] CH1073-112F1 (1), CH1073-445D7 (1)
    frk Encodes: [EST] eu490 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    Genomic GenBank:CU633911 (1) 32344 nt
    Select Tool
    Polypeptide UniProtKB:E7F1M5 (1) 512 aa
    Sequence Information (all 5)
    ORTHOLOGY for frk ( Chr: 20 )
    CITATIONS (19)