ZFIN ID: ZDB-GENE-110411-281
Gene Name: thrombomodulin
Gene Symbol: thbd    Nomenclature History

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Previous Name: si:ch1073-471m19.4

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 20 Mapping Details/Browsers
Description: Predicted to have calcium ion binding activity and transmembrane signaling receptor activity. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in several diseases, including acute kidney failure; atypical hemolytic-uremic syndrome; cerebrovascular disease (multiple); rheumatoid arthritis; and thrombophilia (multiple). Orthologous to human THBD (thrombomodulin).
Genome Resources: Alliance (1),  Ensembl(GRCz11):ENSDARG00000092470 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-thbd N/A 1
PHENOTYPE No data available
DISEASE ASSOCIATED WITH thbd HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
thrombophilia Alliance Thrombophilia due to thrombomodulin defect 614486
{Hemolytic uremic syndrome, atypical, susceptibility to, 6} 612926
DISEASE ASSOCIATED WITH thbd VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process elastic fiber assembly (more)
Cellular Component integral component of membrane (more)
Molecular Function calcium ion binding (more)
GO Terms (all 5)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA thbd-201 (1)    Ensembl 1402
Browsers: EnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM thbd No data available
MARKER RELATIONSHIPS
thbd Contained in: [Fosmid] CH1073-471M19 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
Genomic GenBank:FP017156 (1) 41257 nt
Select Tool
Polypeptide UniProtKB:F8W3I7 (1) 468 aa
ORTHOLOGY for thbd ( Chr: 20 )
CITATIONS (14)