Gene
itga4
- ID
- ZDB-GENE-110411-108
- Name
- integrin alpha 4
- Symbol
- itga4 Nomenclature History
- Previous Names
-
- si:ch73-119a20.1
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to be involved in cell adhesion and integrin-mediated signaling pathway. Predicted to localize to integrin complex. Is expressed in mid cerebral vein and notochord. Human ortholog(s) of this gene implicated in autism spectrum disorder and pancreatic cancer. Orthologous to human ITGA4 (integrin subunit alpha 4).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR018184 | Integrin alpha chain, C-terminal cytoplasmic region, conserved site |
Domain | IPR013649 | Integrin alpha, first immunoglubulin-like domain |
Domain | IPR048285 | Integrin alpha, second immunoglobulin-like domain |
Domain | IPR048286 | Integrin alpha, third immunoglobulin-like domain |
Family | IPR000413 | Integrin alpha chain |
Homologous_superfamily | IPR028994 | Integrin alpha, N-terminal |
Homologous_superfamily | IPR032695 | Integrin domain superfamily |
Repeat | IPR013517 | FG-GAP repeat |
Repeat | IPR013519 | Integrin alpha beta-propellor |
Domain Details Per Protein
Protein | Length | FG-GAP repeat | Integrin alpha beta-propellor | Integrin alpha chain | Integrin alpha chain, C-terminal cytoplasmic region, conserved site | Integrin alpha, first immunoglubulin-like domain | Integrin alpha, N-terminal | Integrin alpha, second immunoglobulin-like domain | Integrin alpha, third immunoglobulin-like domain | Integrin domain superfamily |
---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:A0A8M9Q587
|
752 | |||||||||
UniProtKB:A0A0R4ICS1
|
1018 |
Interactions and Pathways
No data available
Plasmids
No data available