Gene

itga4

ID
ZDB-GENE-110411-108
Name
integrin alpha 4
Symbol
itga4 Nomenclature History
Previous Names
  • si:ch73-119a20.1
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to be involved in cell adhesion and integrin-mediated signaling pathway. Predicted to localize to integrin complex. Is expressed in mid cerebral vein and notochord. Human ortholog(s) of this gene implicated in autism spectrum disorder and pancreatic cancer. Orthologous to human ITGA4 (integrin subunit alpha 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With itga4 Human Ortholog
No data available
Associated With itga4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018184 Integrin alpha chain, C-terminal cytoplasmic region, conserved site
Domain IPR013649 Integrin alpha, first immunoglubulin-like domain
Domain IPR048285 Integrin alpha, second immunoglobulin-like domain
Domain IPR048286 Integrin alpha, third immunoglobulin-like domain
Family IPR000413 Integrin alpha chain
Homologous_superfamily IPR028994 Integrin alpha, N-terminal
Homologous_superfamily IPR032695 Integrin domain superfamily
Repeat IPR013517 FG-GAP repeat
Repeat IPR013519 Integrin alpha beta-propellor
Domain Details Per Protein
Protein Length FG-GAP repeat Integrin alpha beta-propellor Integrin alpha chain Integrin alpha chain, C-terminal cytoplasmic region, conserved site Integrin alpha, first immunoglubulin-like domain Integrin alpha, N-terminal Integrin alpha, second immunoglobulin-like domain Integrin alpha, third immunoglobulin-like domain Integrin domain superfamily
UniProtKB:A0A8M9Q587 752
UniProtKB:A0A0R4ICS1 1018
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA itga4-201 (1) Havana 2270 nt
mRNA itga4-202 (1) Ensembl 3388 nt
mRNA itga4-203 (1) Ensembl 3272 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations