ZFIN ID: ZDB-GENE-110408-4
Gene Name: solute carrier family 6 member 2
Gene Symbol: slc6a2
Sequence Ontology ID : SO:0000704

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Previous Name: si:dkey-182h7.3

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(Including Attributions)
Location: Chr: 7 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have dopamine:sodium symporter activity and norepinephrine:sodium symporter activity; predicted to be involved in dopamine uptake involved in synaptic transmission and norepinephrine  ...
GENE EXPRESSION
All Expression Data: Table 1 from Puttonen et al., 2017
Wild-type Stages, Structures: Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa13869 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21005 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH slc6a2 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    postural orthostatic tachycardia syndrome ?Orthostatic intolerance 604715
    DISEASE ASSOCIATED WITH slc6a2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process NOT dopamine uptake involved in synaptic transmission (more)
    Cellular Component integral component of membrane (more)
    Molecular Function neurotransmitter:sodium symporter activity (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000175 (1)
  • InterPro:IPR037272 (1)
  • PROSITE:PS00610 (1)
  • PROSITE:PS00754 (1)
  • PROSITE:PS50267 (1)
  • Pfam:PF00209 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA slc6a2-001 (1) 5388
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM slc6a2 No data available
    MARKER RELATIONSHIPS
    slc6a2Contained in: [BAC] DKEY-182H7 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_689046 (1) 2605bp
    Genomic GenBank:BX663609 (1) 248960bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1R3H6 (1) 625aa
    Sequence Information (all 7)
    OTHER slc6a2 GENE PAGES
  • Alliance (1)
  • Gene:565776 (1)
  • VEGA:OTTDARG00000035358 (1)
  • Ensembl(GRCz11):ENSDARG00000016141 (2)
  • ORTHOLOGY for slc6a2 (Chr: 7)
    CITATIONS (22)