Gene
slc6a2
- ID
- ZDB-GENE-110408-4
- Name
- solute carrier family 6 member 2
- Symbol
- slc6a2 Nomenclature History
- Previous Names
-
- si:dkey-182h7.3
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have dopamine:sodium symporter activity and norepinephrine:sodium symporter activity. Predicted to be involved in dopamine uptake involved in synaptic transmission and norepinephrine transport. Predicted to localize to neuron projection; neuronal cell body membrane; and presynaptic membrane. Human ortholog(s) of this gene implicated in hypertension and neurocirculatory asthenia. Orthologous to human SLC6A2 (solute carrier family 6 member 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Puttonen et al., 2017
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| postural orthostatic tachycardia syndrome | Alliance | ?Orthostatic intolerance | 604715 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Sodium:neurotransmitter symporter | Sodium:neurotransmitter symporter superfamily |
|---|---|---|---|
|
UniProtKB:F1R3H6
|
625 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
slc6a2-201
(1)
|
Ensembl | 5,388 nt | ||
| mRNA |
slc6a2-202
(1)
|
Ensembl | 5,367 nt |
Interactions and Pathways
No data available
Plasmids
No data available