ZFIN ID: ZDB-GENE-110408-39
Gene Name: cyclic nucleotide gated channel subunit alpha 1b
Gene Symbol: cnga1b    Nomenclature History

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Previous Names: cnga1, si:ch211-149b19.5

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Predicted to have cGMP binding activity; intracellular cAMP-activated cation channel activity; and intracellular cGMP-activated cation channel activity. Predicted to be involved in cation transmembrane transport and visual perception. Predicted to localize to the integral component of membrane. Human ortholog(s) of this gene implicated in retinitis pigmentosa and retinitis pigmentosa 49. Orthologous to human CNGA1 (cyclic nucleotide gated channel subunit alpha 1).
Genome Resources: Alliance (1),  Gene:572249 (1),  Ensembl(GRCz11):ENSDARG00000012125 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa24412 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH cnga1b HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    retinitis pigmentosa 49 Alliance Retinitis pigmentosa 49 613756
    DISEASE ASSOCIATED WITH cnga1b VIA EXPERIMENTAL MODELS No data available
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR000595 Cyclic nucleotide-binding domain
    Domain IPR005821 Ion transport domain
    Homologous_superfamily IPR014710 RmlC-like jelly roll fold
    Conserved_site IPR018488 Cyclic nucleotide-binding, conserved site
    Homologous_superfamily IPR018490 Cyclic nucleotide-binding-like
    Domain IPR032406 Cyclic nucleotide-gated channel, C-terminal leucine zipper domain
    Family IPR032945 cGMP-gated cation channel alpha-1
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cnga1b-201 (1)    Ensembl 2446
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cnga1b No data available
    MARKER RELATIONSHIPS
    cnga1b Contained in: [BAC] CH211-149B19 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_695944 (1)
    Genomic GenBank:CR318612 (1) 149383 bp
    Select Tool
    Polypeptide UniProtKB:X1WH66 (1) 645 aa
    Sequence Information (all 6)
    ORTHOLOGY for cnga1b ( Chr: 23 )
    CITATIONS (19)