ZFIN ID: ZDB-GENE-110405-1
Gene Name: heat shock cognate 70-kd protein, tandem duplicate 2
Gene Symbol: hsp70.2    Nomenclature History

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Previous Names: si:ch73-46h18.6, si:dkeyp-69e1.1, zgc:174006

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have several functions, including ATP binding activity; misfolded protein binding activity; and protein folding chaperone. Predicted to be involved in several processes, including cellular response to unfolded protein; chaperone cofactor-dependent protein refolding; and protein refolding. Predicted to colocalize with COP9 signalosome. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; autoimmune disease of musculoskeletal system (multiple); cystic fibrosis; schizophrenia (multiple); and toxic shock syndrome. Orthologous to human HSPA1L (heat shock protein family A (Hsp70) member 1 like); HSPA1A (heat shock protein family A (Hsp70) member 1A); and HSPA1B (heat shock protein family A (Hsp70) member 1B).
Genome Resources: Alliance (1),  Gene:100535101 (1),  Ensembl(GRCz11):ENSDARG00000092362 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
CRISPR1-hsp70.2
1
PHENOTYPE No data available
DISEASE ASSOCIATED WITH hsp70.2 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH hsp70.2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process cellular response to unfolded protein (more)
Cellular Component cytoplasm (more)
Molecular Function ATP binding (more)
GO Terms (all 18)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA hsp70.2-201 (1)    Ensembl 2302
Browsers: UCSCEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM hsp70.2 No data available
MARKER RELATIONSHIPS
hsp70.2 Contained in: [BAC] CH73-46H18, CH211-11K18 (1), DKEYP-69E1 (1)
hsp70.2 Encodes: [cDNA] MGC:174006 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001362360 (1)
Genomic GenBank:BX511232 171843 nt
Select Tool
Polypeptide UniProtKB:B0UXR9 (1) 643 aa
Sequence Information (all 12)
ORTHOLOGY for hsp70.2 ( Chr: 3 )
CITATIONS (22)