ZFIN ID: ZDB-GENE-110208-9
Gene Name: catenin (cadherin-associated protein), delta 1
Gene Symbol: ctnnd1    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have cadherin binding activity. Involved in cell migration involved in gastrulation; mesodermal cell migration; and posterior lateral line neuromast primordium migration. Predicted to localize to several cellular components, including adherens junction; nucleus; and plasma membrane. Human ortholog(s) of this gene implicated in blepharocheilodontic syndrome 2. Orthologous to human CTNND1 (catenin delta 1).
Genome Resources: Alliance (1),  Gene:556726 (1),  Ensembl(GRCz11):ENSDARG00000078233 (2)
GENE EXPRESSION
All Expression Data: 2 figures from Hsu et al., 2012
Wild-type Stages, Structures: Blastula:512-cell (2.75h-3.0h) to Segmentation:10-13 somites (14.0h-16.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa14184 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa31222 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • uab302 Complex Unknown Unknown CRISPR
    zko827a Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-ctnnd1 1
    CRISPR2-ctnnd1 1
    CRISPR3-ctnnd1 1
    MO1-ctnnd1 N/A 1
    MO2-ctnnd1 N/A 1
    MO3-ctnnd1 N/A 1
    MO4-ctnnd1 N/A 1
    DISEASE ASSOCIATED WITH ctnnd1 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    blepharocheilodontic syndrome 2 Alliance Blepharocheilodontic syndrome 2 617681
    DISEASE ASSOCIATED WITH ctnnd1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell migration involved in gastrulation (more)
    Cellular Component adherens junction (more)
    Molecular Function cadherin binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ctnnd1-201 (1)    Ensembl 4796
    ctnnd1-202 (1)    Ensembl 424
    ctnnd1-204 (1)    Ensembl 552
    ctnnd1-206 (1)    Ensembl 539
    ncRNA ctnnd1-005 (1)    Ensembl 634
    ctnnd1-006 (1)    Ensembl 811
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ctnnd1 No data available
    MARKER RELATIONSHIPS
    ctnnd1 Contained in: [BAC] DKEY-59P5 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_009293418 (1)
    Genomic GenBank:CR848663 (1) 193836 nt
    Select Tool
    Polypeptide UniProtKB:A0A286Y8C1 (1) 931 aa
    Sequence Information (all 26)
    ORTHOLOGY for ctnnd1 ( Chr: 1 )
    CITATIONS (21)