Gene
p2ry12
- ID
- ZDB-GENE-110208-4
- Name
- purinergic receptor P2Y12
- Symbol
- p2ry12 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Is predicted to enable G protein-coupled purinergic nucleotide receptor activity. Involved in G protein-coupled receptor signaling pathway. Acts upstream of or within microglial cell activation. Predicted to be located in membrane. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in asthma; cerebrovascular disease; peripheral artery disease; platelet-type bleeding disorder 8; and type 2 diabetes mellitus. Orthologous to human P2RY12 (purinergic receptor P2Y12).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Mazzolini et al., 2019
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
platelet-type bleeding disorder 8 | Alliance | Bleeding disorder, platelet-type, 8 | 609821 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like | P2Y12 purinoceptor |
---|---|---|---|---|
UniProtKB:E7F2G6
|
345 |
Type | Name | Length (nt) | Analysis |
---|---|---|---|
mRNA |
p2ry12-202
(1)
|
1371 nt |
Interactions and Pathways
No data available
Plasmids
No data available