ZFIN ID: ZDB-GENE-110110-3
Gene Name: bicaudal C homolog 2
Gene Symbol: bicc2    Nomenclature History

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Previous Name: bicc1a (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 14 Mapping Details/Browsers
Description: Predicted to have RNA binding activity. Used to study autosomal dominant polycystic kidney disease. Orthologous to human BICC1 (BicC family RNA binding protein 1).
Genome Resources: Alliance (1),  Gene:402785 (1),  Ensembl(GRCz11):ENSDARG00000076557 (1)
GENE EXPRESSION
All Expression Data: Fig. 2 from Bouvrette et al., 2010
Wild-type Stages, Structures: Cleavage:4-cell (1.0h-1.25h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-bicc2 N/A 1
MO2-bicc2 N/A 1
DISEASE ASSOCIATED WITH bicc2 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH bicc2 VIA EXPERIMENTAL MODELS
Human Disease Fish Conditions Citations
autosomal dominant polycystic kidney disease WT + MO1-bicc2 standard conditions Bouvrette et al., 2010
GENE ONTOLOGY
Ontology GO Term
Molecular Function nucleic acid binding (more)
GO Terms (all 2)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR001660 Sterile alpha motif domain
Domain IPR004087 K Homology domain
Domain IPR004088 K Homology domain, type 1
Homologous_superfamily IPR013761 Sterile alpha motif/pointed domain superfamily
Homologous_superfamily IPR036612 K Homology domain, type 1 superfamily
Domain IPR037974 BICC1, SAM domain
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA bicc2-201 (1)    Ensembl 2976
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM bicc2 No data available
MARKER RELATIONSHIPS
bicc2 Contained in: [BAC] DKEY-201I24 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_203420 (1) 2997 bp
Genomic GenBank:CU468924 (1) 166893 bp
Select Tool
Polypeptide UniProtKB:F1Q505 (1) 849 aa
Sequence Information (all 8)
ORTHOLOGY for bicc2 ( Chr: 14 )
CITATIONS (11)