Gene

selp

ID

ZDB-GENE-110107-2

Name

selectin P

Symbol

selp Nomenclature History

Previous Names

si:ch211-260g14.4

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Description

Predicted to have carbohydrate binding activity and metal ion binding activity. Involved in hematopoietic stem cell migration to bone marrow and hemopoiesis. Predicted to localize to integral component of membrane and plasma membrane. Is expressed in head; trunk; and vascular cord. Human ortholog(s) of this gene implicated in IgA glomerulonephritis; atopic dermatitis; cerebrovascular disease (multiple); and coronary artery disease (multiple). Orthologous to several human genes including SELP (selectin P).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Sun et al., 2010

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Esain et al., 2015
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With selp Human Ortholog

No data available

Associated With selp Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018378	C-type lectin, conserved site
Domain	IPR000436	Sushi/SCR/CCP domain
Domain	IPR000742	EGF-like domain
Domain	IPR001304	C-type lectin-like
Domain	IPR033991	Selectin, C-type lectin-like domain
Family	IPR002396	Selectin superfamily
Family	IPR050350	Complement & Cell Adhesion Regulators
Homologous_superfamily	IPR016186	C-type lectin-like/link domain superfamily
Homologous_superfamily	IPR016187	C-type lectin fold
Homologous_superfamily	IPR035976	Sushi/SCR/CCP superfamily

Domain Details Per Protein

Protein	Length	Complement & Cell Adhesion Regulators	C-type lectin, conserved site	C-type lectin fold	C-type lectin-like	C-type lectin-like/link domain superfamily	EGF-like domain	Selectin, C-type lectin-like domain	Selectin superfamily	Sushi/SCR/CCP domain	Sushi/SCR/CCP superfamily
UniProtKB:E5DV48 InterPro	868

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	selp-201 (1) Ensembl	Ensembl	2,790 nt	Select Tool ZFIN BLAST
mRNA	selp-202 (1) Ensembl	Ensembl	2,611 nt	Select Tool
mRNA	selp-204 (1) Ensembl	Ensembl	834 nt	Select Tool
ncRNA	selp-002 (1) Ensembl	Ensembl	587 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations