Gene

rspo4

ID
ZDB-GENE-110103-2
Name
R-spondin 4
Symbol
rspo4 Nomenclature History
Previous Names
  • si:dkey-107i16.4
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have heparin binding activity. Predicted to be involved in Wnt signaling pathway. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in nonsyndromic congenital nail disorder 4. Orthologous to human RSPO4 (R-spondin 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rspo4 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
nonsyndromic congenital nail disorder 4 Alliance Anonychia congenita 206800
Associated With rspo4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR043601 R-spondin, Fu-CRD domain
Homologous_superfamily IPR009030 Growth factor receptor cysteine-rich domain superfamily
Homologous_superfamily IPR036383 Thrombospondin type-1 (TSP1) repeat superfamily
Repeat IPR000884 Thrombospondin type-1 (TSP1) repeat
Repeat IPR006212 Furin-like repeat
Domain Details Per Protein
Protein Length Furin-like repeat Growth factor receptor cysteine-rich domain superfamily R-spondin, Fu-CRD domain Thrombospondin type-1 (TSP1) repeat Thrombospondin type-1 (TSP1) repeat superfamily
UniProtKB:M5AN99 241
UniProtKB:F8W4P8 246
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations