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Gene

hsd11b1lb

ID
ZDB-GENE-101130-4
Name
hydroxysteroid (11-beta) dehydrogenase 1-like b
Symbol
hsd11b1lb Nomenclature History
Previous Names
  • hsd11b3b
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to enable oxidoreductase activity. Human ortholog(s) of this gene implicated in cortisone reductase deficiency; cortisone reductase deficiency 2; and obesity. Orthologous to several human genes including HSD11B1L (hydroxysteroid 11-beta dehydrogenase 1 like).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Wu et al., 2020
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hsd11b1lb Human Ortholog
No data available
Associated With hsd11b1lb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020904 Short-chain dehydrogenase/reductase, conserved site
Family IPR002347 Short-chain dehydrogenase/reductase SDR
Homologous_superfamily IPR036291 NAD(P)-binding domain superfamily
Domain Details Per Protein
Protein Length NAD(P)-binding domain superfamily Short-chain dehydrogenase/reductase, conserved site Short-chain dehydrogenase/reductase SDR
UniProtKB:E7FCW2
UniProtKB:A0A2R8Q5R7 281
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations