Gene

megf6b

ID

ZDB-GENE-101112-3

Name

multiple EGF-like-domains 6b

Symbol

megf6b Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 11 Mapping Details/Browsers

Description

Predicted to have calcium ion binding activity. Orthologous to human MEGF6 (multiple EGF like domains 6).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Teerlink et al., 2020

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Teerlink et al., 2020
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With megf6b Human Ortholog

No data available

Associated With megf6b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR013032	EGF-like, conserved site
Conserved_site	IPR018097	EGF-like calcium-binding, conserved site
Domain	IPR000742	EGF-like domain
Domain	IPR001881	EGF-like calcium-binding domain
Domain	IPR002049	Laminin-type EGF domain
Domain	IPR011489	EMI domain
Domain	IPR026823	Complement Clr-like EGF domain
Family	IPR042635	MEGF10/SREC1/2-like
Homologous_superfamily	IPR009030	Growth factor receptor cysteine-rich domain superfamily
PTM	IPR000152	EGF-type aspartate/asparagine hydroxylation site

Domain Details Per Protein

Protein	Length	Complement Clr-like EGF domain	EGF-like calcium-binding, conserved site	EGF-like calcium-binding domain	EGF-like, conserved site	EGF-like domain	EGF-type aspartate/asparagine hydroxylation site	EMI domain	Growth factor receptor cysteine-rich domain superfamily	Laminin-type EGF domain	MEGF10/SREC1/2-like
UniProtKB:A0A8M9QIB9 InterPro	1546
UniProtKB:A0A8M9PVQ9 InterPro	1503
UniProtKB:A0A8M3B4A3 InterPro	1589

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	megf6b-201 (1) Ensembl	Havana	5889 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations