Gene

plch2b

ID
ZDB-GENE-101112-1
Name
phospholipase C, eta 2b
Symbol
plch2b Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to have calcium ion binding activity and phosphatidylinositol phospholipase C activity. Predicted to be involved in intracellular signal transduction and lipid catabolic process. Orthologous to human PLCH2 (phospholipase C eta 2).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With plch2b Human Ortholog
No data available
Associated With plch2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR018247 EF-Hand 1, calcium-binding site
Domain IPR000008 C2 domain
Domain IPR000909 Phosphatidylinositol-specific phospholipase C, X domain
Domain IPR001711 Phospholipase C, phosphatidylinositol-specific, Y domain
Domain IPR001849 Pleckstrin homology domain
Domain IPR002048 EF-hand domain
Domain IPR015359 Phosphoinositide-specific phospholipase C, EF-hand-like domain
Family IPR001192 Phosphoinositide phospholipase C family
Family IPR028393 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2
Homologous_superfamily IPR011992 EF-hand domain pair
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily
Homologous_superfamily IPR035892 C2 domain superfamily
Domain Details Per Protein
Protein Length 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 C2 domain C2 domain superfamily EF-Hand 1, calcium-binding site EF-hand domain EF-hand domain pair PH-like domain superfamily Phosphatidylinositol-specific phospholipase C, X domain Phosphoinositide phospholipase C family Phosphoinositide-specific phospholipase C, EF-hand-like domain Phospholipase C, phosphatidylinositol-specific, Y domain PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily Pleckstrin homology domain
UniProtKB:A0A0R4IS51 779
UniProtKB:F1QS65 1011
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations