Gene
dnmbp
- ID
- ZDB-GENE-101026-2
- Name
- dynamin binding protein
- Symbol
- dnmbp Nomenclature History
- Previous Names
-
- tuba (1)
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to have Rho guanyl-nucleotide exchange factor activity. Involved in cilium assembly and kidney development. Predicted to localize to Golgi apparatus; cell-cell junction; and presynapse. Human ortholog(s) of this gene implicated in cataract 48. Is expressed in brain; eye; neuromast; pronephric duct; and pronephric tubule. Orthologous to human DNMBP (dynamin binding protein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Baek et al., 2016
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Baek et al., 2016
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| cataract 48 | Alliance | Cataract 48 | 618415 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR001331 | Guanine-nucleotide dissociation stimulator, CDC24, conserved site |
| Domain | IPR000219 | Dbl homology (DH) domain |
| Domain | IPR001452 | SH3 domain |
| Domain | IPR004148 | BAR domain |
| Domain | IPR035817 | Dynamin-binding protein, first N-terminal SH3 domain |
| Domain | IPR035819 | Dynamin-binding protein, third N-terminal SH3 domain |
| Domain | IPR035820 | Dynamin-binding protein, first C-terminal SH3 domain |
| Family | IPR051492 | Dynamin-binding and Rho GEF |
| Homologous_superfamily | IPR027267 | AH/BAR domain superfamily |
| Homologous_superfamily | IPR035899 | Dbl homology (DH) domain superfamily |
| Homologous_superfamily | IPR036028 | SH3-like domain superfamily |
Domain Details Per Protein
| Protein | Length | AH/BAR domain superfamily | BAR domain | Dbl homology (DH) domain | Dbl homology (DH) domain superfamily | Dynamin-binding and Rho GEF | Dynamin-binding protein, first C-terminal SH3 domain | Dynamin-binding protein, first N-terminal SH3 domain | Dynamin-binding protein, third N-terminal SH3 domain | Guanine-nucleotide dissociation stimulator, CDC24, conserved site | SH3 domain | SH3-like domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:E7F1U2
|
1673 | |||||||||||
|
UniProtKB:A0A8M2B371
|
1392 | |||||||||||
|
UniProtKB:A0A8M3AYH8
|
1589 | |||||||||||
|
UniProtKB:A0A8M2B2P0
|
1667 |
Interactions and Pathways
No data available
Plasmids
No data available