ZFIN is now using GRCz12tu for Genomic Data
Gene
srpk3
- ID
- ZDB-GENE-101025-2
- Name
- SRSF protein kinase 3
- Symbol
- srpk3 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable protein serine/threonine kinase activity. Acts upstream of or within skeletal myofibril assembly. Predicted to be active in cytoplasm and nucleus. Orthologous to human SRPK3 (SRSF protein kinase 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Roychaudhury et al., 2024
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Intellectual developmental disorder, X-linked 114 | 301134 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Family | IPR051334 | Serine/Arginine-Rich Protein Kinases |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/Arginine-Rich Protein Kinases | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8N7TFD0 | InterPro | 731 | |||||
| UniProtKB:A0A8M2BE87 | InterPro | 409 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers