Gene

col4a6

ID
ZDB-GENE-101001-2
Name
collagen, type IV, alpha 6
Symbol
col4a6 Nomenclature History
Previous Names
  • im:7147757
  • shiomaneki (1)
  • sio
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to be an extracellular matrix structural constituent. Involved in axon extension involved in axon guidance and basement membrane organization. Predicted to localize to collagen type IV trimer and extracellular space. Is expressed in several structures, including head; hypodermis; solid lens vesicle; swim bladder; and swim bladder bud. Human ortholog(s) of this gene implicated in AMME complex and X-linked deafness 6. Orthologous to human COL4A6 (collagen type IV alpha 6 chain).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With col4a6 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
X-linked deafness 6 Alliance ?Deafness, X-linked 6 300914
Associated With col4a6 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001442 Collagen IV, non-collagenous
Homologous_superfamily IPR016187 C-type lectin fold
Homologous_superfamily IPR036954 Collagen IV, non-collagenous domain superfamily
Repeat IPR008160 Collagen triple helix repeat
Domain Details Per Protein
Protein Length Collagen IV, non-collagenous Collagen IV, non-collagenous domain superfamily Collagen triple helix repeat C-type lectin fold
UniProtKB:A0A2R8RNY2 1666
UniProtKB:F1QYN1 1714
UniProtKB:A0A1L1QZU7 1666
UniProtKB:Q4TZW7 243
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations